University of Twente Student Theses
Method for manufacturing a hemofiltration fibre mat for use in a combined lung-kidney assist device
Duinmeijer, W.C. (2022) Method for manufacturing a hemofiltration fibre mat for use in a combined lung-kidney assist device.
This is the latest version of this item.
|
PDF
12MB |
| Abstract: | Acute kidney injury (AKI) is a common complication in patients undergoing extracorporeal membrane oxygenation (ECMO). This mainly occurs due to the lung-kidney crosstalk, which means that loss of one of the two organ functions can lead to dysregulation of the other. Preliminary research led us to the hypothesis that a certain number of oxygenator membrane fibre mats could be replaced by hemodiafil-tration membrane fibre mats to accommodate this problem. As no hemodiafiltration fibre mats are cur-rently commercially produced, a mould-based manufacturing method was developed to cater for this need. Fibres are aligned with a predefined interspacing of 0.3 mm in a curved mould and fixated at the ends by using double-sided tape. Thereafter, to combine these mats with oxygenator fibre mats, the fibres are stretched into one horizontal layer and stacked alternately on a potting cap (with oxygenation fibre mats). This stacked membrane bundle can then be potted using the squared potting technique de-veloped by A.F Martins Costa, 2022. |
| Item Type: | Essay (Master) |
| Faculty: | ET: Engineering Technology |
| Subject: | 52 mechanical engineering |
| Programme: | Industrial Design Engineering MSc (66955) |
| Link to this item: | https://purl.utwente.nl/essays/89823 |
| Export this item as: | BibTeX EndNote HTML Citation Reference Manager |
Show download statistics for this publication
Show download statistics for this publicationRepository Staff Only: item control page